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Spectrum: Autism Research News

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Treatments

Efforts to ease the symptoms of autism are beginning to ramp up, with promising candidates in various stages of testing.

May 2012

European consortium strives to spur autism drug development

by  /  21 May 2012

A $38.7 million project in the European Union — the largest single grant for autism research in the world — aims to bring together academic labs and pharmaceutical companies to speed the move from basic to clinical research.

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Early data suggest antibiotic helps treat fragile X syndrome

by  /  19 May 2012

Preliminary results from a placebo-controlled trial of the antibiotic minocycline in children with fragile X syndrome suggest the drug alleviates some aspects of the disorder, according to research presented Friday at the International Meeting for Autism Research in Toronto.

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Shrinking brains

by  /  18 May 2012

Long-term treatment with antipsychotic drugs and mood stabilizers can change the structure of the brain.

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Clinical research: Early interventions improve language

by  /  18 May 2012

Toddlers with autism who receive behavioral interventions that improve joint attention — engaging and following others’ focus — have better language ability five years later than do controls, according to a study published in May in the Journal of the American Academy of Child and Adolescent Psychiatry.

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Giving fathers oxytocin boosts levels in babies

by  /  17 May 2012

Two new studies on oxytocin, the so-called ‘trust hormone,’ suggest new avenues for using the drug to treat autism.

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Fish study links chromosome 16 genes to head size

by  /  17 May 2012

By creating genetically engineered fish, two independent groups have identified genes in an autism hotspot on chromosome 16 that influence head size and brain development. 

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Personalizing medicine

by  /  15 May 2012

A pilot project highlights how adult stem cells could be used to test and select personalized therapies.

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Better tools needed to assess clinical trials

by  /  14 May 2012

The past few years have seen an unprecedented number of clinical trials for experimental drugs to treat autism-related disorders, most notably for fragile X syndrome. But as the trials progress, scientists are calling for better methods to measure the drugs’ effectiveness.

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Trials and tribulations

by  /  11 May 2012

Clinical trials for fragile X drugs should include a behavioral therapy component, says a parent of a child with the disorder.

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Defects in carnitine metabolism may underlie autism

by  /  10 May 2012

A genetic defect in the synthesis of carnitine, a molecule that is essential for proper mitochondrial function, might slightly increase risk for autism in some children, according to research published 8 May in the Proceedings of the National Academy of Sciences.

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