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Spectrum: Autism Research News

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Treatments

Efforts to ease the symptoms of autism are beginning to ramp up, with promising candidates in various stages of testing.

July 2012

Clinical research: Autism diagnosis stable over time

by  /  24 July 2012

Nearly all children diagnosed with autism retain their diagnosis when screened again at 8 years of age, according to a population-based study of more than 1,000 children, published in June in the Journal of Developmental Behavioral Pediatrics.

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Gene therapy

by  /  20 July 2012

Delicate dosage issues are just one complication of developing gene therapy for neurodevelopmental disorders.

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Cost comparison

by  /  17 July 2012

Early intensive behavioral therapy could save more than a million dollars over the lifetime of an individual with autism.

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Targeting brain microcircuits may help treat autism

by  /  10 July 2012

Understanding the function of neuronal circuits, specifically microcircuits in the prefrontal cortex and elsewhere in the brain, will play a major role in translating research findings into new autism treatments, says Vikaas Sohal.

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A young boy is sitting up in bed and wiping his left eye with his left hand.

Clinical research: Melatonin relieves sleep problems in autism

by  /  4 July 2012

Children who receive a combination of melatonin and behavioral therapy fall asleep faster and have better sleep quality than those who get either treatment alone or those on placebo, according to a study published 22 May in the Journal of Sleep Research.

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Growth factor

by  /  3 July 2012

A small clinical trial at the Seaver Autism Center at Mount Sinai aims to test whether an existing drug, the growth factor IGF-1, will help treat some of the core symptoms of autism in children with a specific genetic mutation.

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June 2012

SHANK2 mouse models show opposite brain signaling

by  /  25 June 2012

Two new strains of mice carrying different mutations in the SHANK2 gene show similar autism-like behaviors but opposing effects on brain signaling, according to two independent studies published 14 June in Nature.

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Cognition and behavior: Context affects repetitive behavior

by  /  20 June 2012

Repetitive behaviors are often motivated by anxiety when children with autism and intellectual disability transition from one task to the next, but they are linked to a desire for attention when the children have free time, according to a study published in May in the Journal of Applied Research in Intellectual Disabilities.

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Drug merger

by  /  19 June 2012

Seaside Therapeutics, a small biotech, and Swiss pharmaceutical giant Roche have announced a partnership to develop drugs for fragile X syndrome and autism.

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Clinical research: Genetic variant improves effects of oxytocin

by  /  15 June 2012

Men with a common autism-linked variant of CD38, a gene that regulates levels of the ‘trust hormone’ oxytocin, benefit more from the hormone than do those with other variants, according to a study published in the May issue of Neuropsychopharmacology.

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