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Spectrum: Autism Research News

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Treatments

Efforts to ease the symptoms of autism are beginning to ramp up, with promising candidates in various stages of testing.

January 2022
Visual stimulus of 4 circles with black and white stripes.

Visual task flags autistic people who respond to GABA agonists

by  /  5 January 2022

The investigational drug arbaclofen makes autistic people’s brains respond to a visual task more like non-autistic people’s brains do.

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Motor skills in autism: A missed opportunity

by ,  /  4 January 2022

Motor differences are more relevant than has historically been appreciated for understanding, assessing and supporting people on the spectrum.

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December 2021

Cluster of traits tied to rare mutations in autism-linked gene

by  /  20 December 2021

Developmental delay, intellectual disability and behavioral issues are common among people who have mutations in MYT1L, a gene with strong ties to autism.

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Illustration of DNA helix highlighting the methylation process.

DNA methylation in autism, explained

by  /  13 December 2021

How chemical tags called methyl groups position themselves on genetic sequences may hint at some of the causes of autism.

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Illustration of hybrid objects: part light bulb, part lab vial, some in blue and some in red to signify null and replicated results

Null and Noteworthy: Quality of life, IACC discussion, mixed results on interventions

by  /  2 December 2021

In this edition of Null and Noteworthy, the Interagency Autism Coordinating Committee grapples with “groundbreaking” research and two reviews of interventions come to conflicting conclusions.

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November 2021
Dr. Shafali Jeste portrait with a vibrant fuschia background.

Shafali Jeste: Early autism meets its match

by  /  30 November 2021

Shafali Jeste has spent the bulk of her scientific career searching for biological markers of autism. Her goal: to improve lives through early diagnosis and speedy testing of therapies.

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UBE3A expression in mouse brain slices, shown in green.

One-shot gene therapy for Angelman syndrome shows promise in mice

by  /  29 November 2021

A potential new gene therapy delivered via a single injection mimics ratios of proteins normally found in cells.

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Professor Andrew Whitehouse surrounded by playful children in the busy clinic in Subiaco Western Australia.

Beyond the bench: A conversation with Andrew Whitehouse

by  /  24 November 2021

Andrew Whitehouse talks about his conservation efforts in the Australian Outback, what it’s like to be an identical twin and why he leaves work promptly at 5 p.m.

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Pink, blue and purple illustration shows a cell with mitochondria.

Mitochondria: An energy explanation for autism

by  /  22 November 2021

People with autism have more mutations than others do in both mitochondrial DNA and nuclear DNA that affects mitochondrial function.

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Cognitive behavioral therapy may be only mildly effective for anxious, autistic children

by  /  16 November 2021

Many autistic children rate the therapy as less effective at treating their anxiety than their parents and clinicians do.

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