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Spectrum: Autism Research News

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The Brain

Charting the structure and function of the brain’s many circuits may unravel autism’s mysteries.

July 2012

Cognition and behavior: Maternal infection linked to anxiety

by  /  18 July 2012

Offspring born to pregnant rats with an activated immune system emit more distress calls when they receive electrical shocks than do controls, according to a study published 9 June in the Journal of Psychiatric Research.

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Genetics: Language disorder gene linked to autism

by  /  17 July 2012

A girl with autism has a spontaneous deletion in CMIP, a gene associated with specific language impairment, providing another genetic link between the two disorders. The case study was published 11 June in Autism Research.

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Maternal antibodies may affect brain size in autism

by  /  12 July 2012

The action of certain maternal antibodies on the fetal brain may underlie the large brain size seen in some children with autism, according to preliminary findings from both monkey and human studies presented at a conference in Boston last week.

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Expression data links gene candidates to autism

by  /  11 July 2012

Identifying genetic variants that affect the expression of other genes can enhance traditional gene association analyses and highlight candidate risk factors for autism, according to a study published 16 May in Molecular Autism.

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Molecular mechanisms: FMRP target linked to cognitive skills

by  /  11 July 2012

The protein missing in people with fragile X syndrome may activate the expression of a signaling protein dubbed NOS1 during prenatal development of brain regions involved in language and social skills, according to a study published 11 May in Cell.

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Brain’s bluff

by  /  10 July 2012

Studying how and when people bluff during a poker game could help us understand how people make social decisions, according to an article in Science. The same approach could also be used to study social deficits in autism.

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Targeting brain microcircuits may help treat autism

by  /  10 July 2012

Understanding the function of neuronal circuits, specifically microcircuits in the prefrontal cortex and elsewhere in the brain, will play a major role in translating research findings into new autism treatments, says Vikaas Sohal.

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Cognition and behavior: Hearing delay unique to autism

by  /  10 July 2012

An abnormal response to sound detected by brain imaging may distinguish children with autism from those with specific language impairment, according to a study published 30 May in Neuroreport.

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Exome sequencing identifies unknown disorders

by  /  9 July 2012

By sequencing the protein-coding region of the genome of a single affected family member, researchers were able to diagnose 20 percent of people in 85 consanguineous families with unknown neurodevelopmental disorders, according to research published 13 June in Science Translational Medicine.

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Brain hack

by  /  6 July 2012

The Allen Institute convened a five-day ‘hackathon’ to create new tools that take advantage of the petabytes of brain mapping data in the institute’s massive databases.

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