Signs & Symptoms

Autism’s core symptoms accompany a constellation of subtle signs that scientists are just beginning to unmask.

Gathering girls: Researchers find more girls with autism when they actively look for them.Westend61 / Getty Images

Estimate of autism’s sex ratio reaches new low

by  /  27 April 2017
A massive new analysis drops the ratio of boys to girls who qualify for an autism diagnosis to about 3-to-1.
Checking connections: Bundles of neurons called white-matter tracts bridge far-flung, and nearby, regions of the brain.

Two autism features may share common root in brain

by  /  26 April 2017
Children with autism who have both severe repetitive behaviors and sensory sensitivities tend to have had unusually structured nerve tracts in infancy.
Common cause: Many people with mutations in a gene called TRIP12 share characteristic features.

Rare mutation linked to autism affects language ability

by  /  24 April 2017
Mutations in a gene called TRIP12 — which is involved in tagging proteins for destruction — can lead to intellectual disability, language delay and autism.
April 2017
Telltale teeth: Tony, who has an ADNP mutation, had 16 teeth when he was 13 months old. Courtesty of Sandra Sermone

Precocious baby teeth signal rare form of autism

by  /  20 April 2017

Most children with a rare autism-linked mutation develop baby teeth one to two years earlier than usual.

Features / Deep Dive

Autism’s drug problem

by  /  19 April 2017

Many people on the spectrum take multiple medications — which can lead to serious side effects and may not even be effective.

Culture clash: Parents of children with autism in Japan are more likely than those in four other countries to say their children have intellectual difficulties.Masaru123 / iStock

Parent reports of autism features vary by country

by  /  13 April 2017

Parents in the United States tend to rate their children’s autism features as more severe than do parents in four other countries.

Social subtleties: Some doctors say that girls with autism are socially savvier than boys, but the science is inconsistent. Hero Images / Getty Images

Sex differences among people with autism may be minimal

by  /  12 April 2017

Autism looks similar in girls and boys, suggest results from a large study.

1 Comment
Illustration by Bee Johnson
Opinion / Viewpoint

Early brain enlargement augurs distinct form of autism

by  /  11 April 2017

A minority of boys with autism have brains that are unusually large relative to their bodies — a trait tied to regression and intellectual disability.

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Pill plot: Medications can ease irritability, aggression and other challenging behaviors in children with autism, but they have side effects.TongRo Images     
/ Getty Images

Children with autism may forego behavioral therapy for meds

by  /  10 April 2017

Many children with autism who take antipsychotic medications do not receive behavioral therapy.

Dazzling display: Children with autism often show unusual sensory behaviors, such as a fascination with lights.Solovyova /
News / Toolbox

Parent survey quantifies sensory quirks in autism

by  /  7 April 2017

A new questionnaire reveals the frequency and impact of sensory sensitivities in children with autism.

Digital difference: Adapting screening measures for tablets may boost efforts to flag autism in the doctor’s office.Hero Images / Getty Images

Screening status quo misses most children with autism

by  /  3 April 2017

Most children with autism go undiagnosed until after age 3, and many of these children remain undiagnosed until after they reach school age.

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March 2017
Features / Deep Dive

The twenty-something free fall

by  /  29 March 2017

Young adults with autism face many new expectations and challenges — with none of the support that is available during high school.

Delayed action: Children with autism who have de novo mutations in key autism genes tend to walk later than other children with the condition. HIKARU VISION / Getty Images

Rare autism mutations linked to distinct sets of features

by  /  29 March 2017

Children who carry certain rare mutations linked to autism learn to walk late — but have less severe social and language difficulties than do other children with the condition.


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