This year’s list of top papers highlights nuances in the genetics of autism and new leads on early treatment.
Rare or common, inherited or spontaneous, mutations form the core of autism risk.
Success in a small clinical trial of spinal muscular atrophy suggests gene therapy might treat single-gene conditions related to autism.
The combinations of genetic variants that influence social communication may vary throughout childhood and adolescence.
Deletions within a specific segment of chromosome 22 may raise the risk of autism.
Two new methods allow scientists to swap single bases in DNA or RNA sequences.
Deleting KCTD13, a gene in the autism risk region 16p11.2, has little effect on brain or head size in mice — contradicting results from a 2012 zebrafish study.
Older men and women are more likely than young ones to have a child with autism, but this connection is not straightforward.
A new trick involving a virus gives the CRISPR enzyme system the ability to edit the genome of a neuron more predictably than was previously possible.
Spectrum Wiki is a community of researchers affiliated with an academic or research institutions. To be considered for participation, please fill out this form and a member of our team will respond to your request.