TOPIC

Genes

Rare or common, inherited or spontaneous, mutations form the core of autism risk.

November 2017
News

Fragile X behaviors may stem from gene’s loss in specific cells

by  /  13 November 2017

Deleting FMR1, the gene mutated in fragile X syndrome, in subsets of mouse neurons leads to distinct features of the condition.

0 Comments
News

Brain cells spun from skin point to subtypes of autism

by  /  12 November 2017

Neurons derived from people with a syndromic form of autism look and behave differently than do those from people with classic autism.

1 Comment
News

Distinct set of genes controls brain activity in people with autism

by  /  12 November 2017

A different set of genes regulates brain activity in people with autism than the set involved in controls.

1 Comment
News

Imaging study links immune genes to anxiety

by  /  12 November 2017

Mice missing any of 11 genes involved in the immune response show differences in brain anatomy that track with anxiety.

0 Comments
News

SHANK3 zebrafish may be too cool for schools

by  /  12 November 2017

Zebrafish lacking the autism-linked gene SHANK3 show little social interest and other behavioral abnormalities.

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News

Gene therapy technique prevents seizures in Angelman mice

by  /  12 November 2017

Introducing the gene UBE3A into neurons that dampen brain activity prevents seizures in a mouse model of Angelman syndrome.

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News

Human ‘mini-brains’ make themselves at home in mice

by  /  11 November 2017

Spheres of brain cells derived from people and implanted into mouse brains recruit blood vessels and integrate with mouse neurons.

2 Comments
News

Reactions from SfN 2017

by  /  9 November 2017

Spectrum heads to Washington, D.C., to cover the annual Society for Neuroscience conference.

1 Comment
News

Registry for autism-linked syndrome spurs new research

by  /  2 November 2017

Nine U.S. clinics are pooling their data to create a registry of people who have an extra copy of a region on chromosome 15 called 15q11-13, a genetic abnormality often found in people with autism.

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October 2017
News

Mosaic mutations in sperm point to increased autism risk

by  /  23 October 2017

More than 5 percent of mutations thought to have arisen spontaneously in a child with autism may in fact be inherited.

1 Comment
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