TOPIC

Genes

Rare or common, inherited or spontaneous, mutations form the core of autism risk.

Features / Webinars

Journal club: Exploring treatments for Rett syndrome

11 December 2017
Register for the next Spectrum journal club, which will feature two papers about therapies that adjust levels of the Rett syndrome protein MECP2.
News / Toolbox

New technique ramps up editing of genes in stem cells

by  /  17 November 2017
A novel method allows researchers to rapidly generate stem-cell colonies with mutations linked to autism or other conditions.
News

Study bolsters genetic link between arthritis, autism

by  /  16 November 2017
Men and women with rheumatoid arthritis, an autoimmune condition, are at increased risk of having a child with autism.
November 2017
News

Map of microglia in mouse brain may reveal role in autism

by  /  15 November 2017

Researchers have mapped how immune cells in the brain called microglia change with age in mice.

1 Comment
News

Chromosome 16 deletion miswires brain in people, mice

by  /  14 November 2017

Mice and people missing a copy of a chromosomal region called 16p11.2 show similar patterns of weak brain connections.

0 Comments
News

Rett syndrome mutation’s effects vary by cell type

by  /  14 November 2017

Mutations in the Rett syndrome gene MECP2 have different effects on subtypes of neurons.

0 Comments
News

‘Mini-brains’ mirror fetal brain development

by  /  14 November 2017

Spheres of brain cells derived from a fetal skull have gene expression patterns similar to those in brain tissue from the same fetus.

0 Comments
Opinion / Viewpoint

Electronic glow may disrupt sleep for people on the spectrum

by  /  13 November 2017

Exposure to certain types of light at night may exacerbate sleep issues among people with autism.

0 Comments
News

Autism may disrupt the body’s circadian clock

by  /  13 November 2017

Sleep problems in autism may stem from the same biological changes that underlie the core features of the condition.

0 Comments
News

Note to autism scientists: Control for z’s

by  /  13 November 2017

Differences in sleep and circadian rhythm may distort the results of autism studies.

1 Comment
News

Fragile X behaviors may stem from gene’s loss in specific cells

by  /  13 November 2017

Deleting FMR1, the gene mutated in fragile X syndrome, in subsets of mouse neurons leads to distinct features of the condition.

0 Comments
News

Brain cells spun from skin point to subtypes of autism

by  /  12 November 2017

Neurons derived from people with a syndromic form of autism look and behave differently than do those from people with classic autism.

1 Comment
News

Distinct set of genes controls brain activity in people with autism

by  /  12 November 2017

A different set of genes regulates brain activity in people with autism than the set involved in controls.

1 Comment
close

Log in to your Spectrum Wiki account

Email Address:

Password:


close

Request your Spectrum Wiki account

Spectrum Wiki is a community of researchers affiliated with an academic or research institutions. To be considered for participation, please fill out this form and a member of our team will respond to your request.

Name:

Email Address:

Title and Lab:

Area of Expertise:

Comments: