TOPIC

Genes

Rare or common, inherited or spontaneous, mutations form the core of autism risk.

News

Genes altered in autism may control brain’s thickness

by  /  12 April 2018
Some genes associated with autism may influence the thickness of the cerebral cortex, the brain’s outer layer.
News

Loss of autism gene makes mice sensitive to pain

by  /  9 April 2018
Mice lacking CNTNAP2, a gene strongly linked to autism, are acutely sensitive to pain.
Multimedia / Webinars

Webinar: Feng Zhang discusses genome editing in autism research

6 June 2018
Register for the next Spectrum webinar, featuring Feng Zhang, who will discuss genome editing in autism research.
April 2018
News

Mounting evidence links mitochondrial DNA to autism

by  /  5 April 2018

Genetic variants that affect mitochondria, the organelles that power cells, may increase the risk of autism.

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News

Gene in autism risk region plays key role in brain development

by  /  4 April 2018

Mice missing TAOK2, a gene in a segment of chromosome 16 linked to autism, have big brains, immature neuronal junctions and asocial behavior.

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News

Cancer drug shows promise for treating some forms of autism

by  /  2 April 2018

A low dose of a drug used to treat lymphoma may ease social problems in some forms of autism.

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March 2018
News

Gene on chromosome 16 may be valuable player in autism

by  /  29 March 2018

Deleting one copy of a gene called MVP impairs the brain's ability to adapt to changes in the environment.

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Opinion / Viewpoint

Explaining ‘resilience’ in autism may seed new therapies

by  /  27 March 2018

Some individuals who have autism mutations show no signs of the condition; understanding why may lead to treatments.

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News / Toolbox

New tools speed genome assembly, tests of gene function

by  /  23 March 2018

Two new techniques could help reveal the molecular basis of conditions such as autism.

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Opinion / Viewpoint

How variability among mouse strains can aid autism research

by  /  21 March 2018

Researchers can convert the distinct genetic backgrounds of lab mice from a problem to an advantage, exploiting the differences to advance our understanding of autism.

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News

Studies pinpoint key gene in region linked to autism

by  /  21 March 2018

A single gene, OTUD7A, may account for most of the features seen in people missing a segment of chromosome 15 known as 15q13.3.

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Mouse in a lab or maze hops around sniffing here and there
Features / Deep Dive

Why studying autism in mice may be doomed to fail

by  /  21 March 2018

After more than a decade of effort, scientists are questioning whether mouse models of autism can ever capture the social deficits seen in people with the condition.

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Opinion / Viewpoint

‘Outdated’ mouse model exposes key disruptions in autism brain

by  /  21 March 2018

A mouse model based on exposure to an epilepsy drug offers a useful window into the brain circuits altered in autism.

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