TOPIC

Genes

Rare or common, inherited or spontaneous, mutations form the core of autism risk.

News

Rat study ties Rett syndrome gene to pain processing

by  /  21 September 2017
Mutations in MECP2, the gene mutated in Rett syndrome, may alter the proportions and activity of sensory neurons in rats.
News

Parental age ups rate of new mutations passed to children

by  /  20 September 2017
Men and women both transmit an increasing number of new mutations to their children as they age.
Opinion / Q&A

‘Antisocial’ bees point to ancient roots for some autism genes

by ,  /  19 September 2017
Honey bees that fail certain social tests have genetic profiles similar to those of people with autism.
September 2017
News / Toolbox

Method that maps DNA tags reveals new types of neurons

by  /  15 September 2017

A new technique classifies neurons by surveying chemical tags that turn genes on or off on the neurons’ DNA.

0 Comments
News

Sizeable fraction of autism risk traced to ‘mosaic’ mutations

by  /  14 September 2017

Mutations that appear in only some of the body’s cells contribute to autism in about 4 percent of people with the condition.

3 Comments
Features / Webinars

Journal club: Mosaic mutations in autism

9 October 2017

Register for the first Spectrum journal club, which will feature presentations about two papers on mosaic mutations in autism.

0 Comments
Opinion / Viewpoint

Protein factories at neuronal junctions take center stage in autism

by ,  /  12 September 2017

Some genes linked to autism regulate the production of proteins at neuronal junctions, suggesting that disrupted protein synthesis contributes to the condition.

0 Comments
August 2017
News

Sibling study bolsters role of common variants in autism

by  /  24 August 2017

Children with autism are genetically more similar to one another than to a group of unaffected siblings.

0 Comments
News / Toolbox

Whole genomes may power search for autism risk factors

by  /  23 August 2017

Scientists this week announced the release of nearly 7,000 whole-genome sequences from a collection of families that each have one child with autism.

0 Comments
News

Social interactions shape gene expression in fragile X mice

by  /  16 August 2017

Mice missing FMR1, the gene mutated in fragile X syndrome, have an atypical brain response to meeting an unfamiliar mouse.

0 Comments
News / Toolbox

Method lights up active genes in fruit fly brains

by  /  11 August 2017

A new technique illustrates how mutations associated with autism affect gene expression at different stages of development in the fly brain.

0 Comments
News

Genetic risk factors for autism may affect family size

by  /  10 August 2017

People who carry risk factors for autism but do not have the condition tend to have slightly fewer children than average, and have them later in life.

2 Comments
News

Scan of ‘missense’ mutations marks new suspects for autism risk

by  /  9 August 2017

A large study of minute mutations in people with developmental conditions, including autism, has uncovered 200 potential risk genes.

0 Comments
close

Log in to your Spectrum Wiki account

Email Address:

Password:


close

Request your Spectrum Wiki account

Spectrum Wiki is a community of researchers affiliated with an academic or research institutions. To be considered for participation, please fill out this form and a member of our team will respond to your request.

Name:

Email Address:

Title and Lab:

Area of Expertise:

Comments: