A gene therapy for Angelman syndrome stands at the forefront of efforts to treat autism-linked conditions that stem from single genes.

A growing number of studies are revealing circuits that may underlie social challenges in autism — and how to fine-tune them.

Some families do not have the financial ability or time to participate in clinical trials for autism. New technologies may enable them to participate from their homes.

Blocking one form of an enzyme implicated in autism eases unusual behaviors and seizures in mice missing a top autism gene.

Autism and epileptic seizures often go hand in hand. What explains the overlap, and what does it reveal about autism’s origins?

Tuberous sclerosis provides a unique opportunity to understand autism because about half of people with that single-gene condition also have autism.

Certain patterns of electrical activity in the brain may signal autism in children with tuberous sclerosis complex, a related genetic condition.

A drug that treats tumors and epilepsy in people with tuberous sclerosis complex does not boost their intelligence or ease autism traits.

A website called GeneMatcher has helped researchers identify a new gene for intellectual disability, developmental delay and autism.

An analysis of four mouse models negates certain assumptions underlying the signaling imbalance theory of autism.