The U.S. Food and Drug Administration plans to make an approval decision on the first-ever drug for girls and women with Rett syndrome by 12 March.

Time is running out to expose this disreputable push for profit over care and change insurance, funding and training practices for the better.

Both human and mouse progenitor cells with the alterations struggle to become neurons and instead express genes that are typically active only in muscle or the heart.

The treatment eases the animals’ sleep troubles, suggesting it has clinically meaningful effects beyond what was thought to be a critical window in early life.

Cells from people with fragile X syndrome overproduce — but don’t accumulate — proteins. New work suggests that excessive protein breakdown may account for this discrepancy, and explain some of the syndrome’s traits.

To include more autistic people in research, here’s what scientists need to know about informed consent procedures for study participants who have impaired decision-making capacity.

This edition takes aim at the autism-intervention evidence base with a slew of null results, plus findings that challenge a prevailing autism brain theory.

In light of growing evidence that motor challenges are common among people with autism, we asked five researchers how these problems fit into the definition of the condition.

This month’s newsletter highlights findings on the use of three medication types during pregnancy.

The in-depth approach shows mutations in the autism-linked gene disrupt neuronal growth and communication, as well as mitochondrial gene expression.