New method probes genes’ function in brain organoids
A screening technique tests how inactivated genes affect spheres of cultured brain cells; it could shed light on autism-linked mutations.
A screening technique tests how inactivated genes affect spheres of cultured brain cells; it could shed light on autism-linked mutations.
Neurons derived from people with 22q11.2 deletion syndrome show deficits in calcium signaling and electrical activity, pointing to possible therapeutic targets.
An infusion of umbilical cord blood does not improve social skills in autistic children, according to results from the largest, most rigorous test of the therapy for autism to date.
Researchers have monitored the active genome in brain organoids over the course of nearly two years — and may find clues to autism’s roots.
The mutation that causes Angelman syndrome makes neurons hyperexcitable, which may explain the frequent seizures that most people with the syndrome have.
Here are seven Spectrum stories from this year that deserve a close look.
Two agency letters put California-based Liveyon on warning and alert the public to the risks associated with stem-cell based therapies for autism.
A new technique allows researchers to transplant human microglia into mouse brains and better study the association between these cells and autism.
Researchers have analyzed thousands of brain organoids derived from six autistic people, gaining the potential to rapidly screen drugs.
New findings hint at why drugs that work in mouse models of fragile X syndrome have not been effective in people.