Tag: stem cells

January 2017
Tissue tiers:  Intestinal organoids have layered folds (left) like those in the human gut, and working neurons (right, green).
News / Toolbox

Neurons talk to muscle cells in tiny test-tube intestine

by  /  6 January 2017

A new method allows researchers to transform stem cells into miniature intestines with a working nervous system.

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November 2016
Short circuit: Stem cells derived from people with Angelman syndrome do not develop mature electrical firing patterns.
News

Faulty electrical activity keeps Angelman syndrome cells apart

by  /  16 November 2016

A new stem cell model of Angelman syndrome delivers evidence for three molecular mechanisms underlying the condition — and one potential treatment.

0 Comments
Lab spheres: Organoids contain different types of cells arranged in layers similar to those found in the human brain.
News

‘Mini-brains’ may mimic only early brain development

by  /  15 November 2016

Gene expression in so-called ‘organoids’ resembles the pattern seen in the first few weeks of a developing brain.

0 Comments
Signaling spheres: Neurons derived from skin cells communicate with each other in brain-like spheres.
News

Merging ‘mini-brains’ recapitulates brain’s electrical balance

by  /  15 November 2016

Fusing two spheres of neurons that either ramp up or tamp down brain activity yields neural networks like those in the developing brain.

0 Comments
Brain boost: An injection of stem cells can improve cognition in rats. 
© The Sanger Institute. Wellcome Images
News

Stem cell transplant makes rats more social

by  /  14 November 2016

Injecting stem cells into young rats makes them more social and flexible when learning tasks than before the treatment.

0 Comments
October 2016
Structural issues: Neurons carrying mutations in Rett syndrome genes may have defects in microtubules (red), which form the cell skeleton. Robert S. McNeil / Science Source
News

Drug duo may reverse effects of Rett mutations in cells

by  /  21 October 2016

A pair of existing drugs normalizes the appearance and activity of neurons derived from the skin of individuals with Rett syndrome.

3 Comments
muotri844
Features / Webinars

Webinar: Alysson Muotri discusses stem cell research in autism

19 October 2016

Register now for the next Spectrum webinar, featuring Alysson Muotri, who will discuss how stem cell research can provide insight into human neurodevelopment and the social brain.

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Mighty mimics:  Laboratory-grown microglia, the brain’s immune cells, could offer clues to Rett syndrome.Rudolph Jaenisch
News / Toolbox

Chemical cocktail creates microglia on demand

by  /  14 October 2016

A new method transforms lab-made stem cells into microglia, the brain’s immune cells.

0 Comments
September 2016
daniel_hertzberg_seekers_opener_final3
Features / Deep Dive

The seekers: Why parents try fringe therapies for autism

by  /  21 September 2016

Many parents resort to unproven — even dangerous — alternative treatments for their children’s autism. What drives them?

21 Comments
Making connections: Neurons derived from the dental cells of a child with Williams syndrome form more synapses than usual (yellow).
News

Tooth fairy delivers drug target for boosting social interest

by  /  16 September 2016

Cells derived from the dental pulp of children with Williams syndrome hint at a treatment approach for autism.

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