Tag: simplex families

July 2017
News

Large study shines spotlight on ‘mosaic’ mutations in autism

by  /  19 July 2017

About 8 percent of non-inherited mutations in people with autism occur in only some of the body’s cells, according to a study of 20,000 people.

0 Comments
December 2016
News

Mutations in mitochondria genes may raise autism risk

by  /  22 December 2016

Some children with autism carry harmful mutations in the DNA found in mitochondria, the cell’s energy producers.

2 Comments
October 2016
News

Nature of risk mutations varies with families’ history of autism

by  /  10 October 2016

Large autism-linked mutations tend to be inherited in families with a history of the condition. By contrast, they often arise spontaneously in families with a single affected person.

1 Comment
November 2015
News

Three sets of traits in siblings signal autism’s heritability

by  /  26 November 2015

A study of more than 2,500 families that have at least one child with autism has found three factors that predict autism symptoms in an unaffected sibling.

0 Comments
News

Some genetic repositories may put private details at risk

by  /  5 November 2015

An online portal designed to give researchers easy access to genomic data may unwittingly reveal some sensitive information.

0 Comments
June 2015
News

Some behavioral problems in autism may stem from poor health

by  /  11 June 2015

Many children with autism have gastrointestinal problems, seizures and sleep disorders. A new study suggests that these seemingly disparate conditions are interconnected and may lead to the children’s behavioral issues.

8 Comments
February 2015
News

Some sibling sets arrive at autism with different mutations

by  /  5 February 2015

Less than one-third of sibling pairs with autism who carry rare mutations in autism-linked genes share those mutations, according to the largest study yet to sequence whole genomes of people with the disorder. The study questions the assumption that autism’s risk factors run in families, but some experts are skeptical.

6 Comments
December 2014
Features / Special Reports / 2014 Year in review

Notable papers of 2014

22 December 2014

It’s no easy feat to whittle down the list of the most influential autism papers to a mere 10. So please consider this but a taste of the burgeoning field, presented in chronological order and based on suggestions from many researchers.

0 Comments
November 2014
News

Rare mutations linked to severity of autism symptoms

by  /  3 November 2014

Boys with autism who carry rare, spontaneous mutations have lower intelligence quotients and more severe symptoms than do those who may have inherited the disorder. The finding, published 21 October in the Proceedings of the National Academy of Sciences, hints at two classes of autism risk with varying severity.

10 Comments
October 2014
News

Massive sequencing studies reveal key autism genes

by  /  29 October 2014

Analyzing the sequences of more than 20,000 people, researchers have unearthed the largest and most robust list of autism genes so far, they reported today in Nature.

8 Comments
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