This article is also available in anglais. Il y a quelques années la mère d’un jeune autiste m’a téléphoné. Elle venait d’apprendre que son fils, qui était dans la vingtaine, avait une délétion de SHANK3, l’un des gènes qui, d’après les découvertes de mon équipe, subit une mutation chez certaines personnes autistes. Cette nouvelle m’a […]

Variants that control gene expression are often involved in whether a mutation ends up being harmful, and how harmful it is.

To find variants between genes that contribute to autism, researchers may need thousands more whole genomes than they have now.

Genetic variants that affect mitochondria, the organelles that power cells, may increase the risk of autism.

Some individuals who have autism mutations show no signs of the condition; understanding why may lead to treatments.

Scientists campaign for elected office in record numbers, folate autoantibodies are common in autism families, and neurons form a genetic mosaic in the brain.

People with autism who have rare, damaging mutations tend to have low scores on intelligence tests.

Children with autism may have an excess of spontaneous mutations in DNA that controls the expression of autism genes.

About 17 percent of children with autism are calmer and more communicative than usual when they have a fever.

Mutations that appear in only some of the body’s cells contribute to autism in about 4 percent of people with the condition.