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Spectrum: Autism Research News

Tag: signaling imbalance

July 2017

Antidepressant eases some autism features in mice

by  /  28 July 2017

A drug that keeps neurons bathed in the chemical messenger serotonin prevents social abnormalities in a mouse model of dup15q syndrome.

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Drug that shifts brain’s signaling balance could treat autism

by  /  20 July 2017

A drug that alters the balance of two key chemical messengers in the brain may help treat autism, suggests a proof-of-principle study.

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March 2017

In trials, repurposed drug shows promise for autism

by  /  27 March 2017

A drug used to treat excessive swelling seems to ease autism features in some children on the spectrum.

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February 2017

Distinct mutations in sodium channel trigger autism, epilepsy

by  /  8 February 2017

Some mutations in a gene called SCN2A make neurons less excitable and are linked to autism; others have the opposite effect and may cause seizures during infancy.

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January 2017

Exploring the hidden world of inhibitory brain signals

by ,  /  24 January 2017

Scientists have discovered more than 100 new proteins at junctions in the brain that dampen neuronal activity.

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Diverse causes of autism converge on common gene signature

by  /  23 January 2017

The brains of people with autism show a distinct molecular signature that reflects alterations in how genes are pieced together and expressed.

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November 2016

New treatment for Rett syndrome targets cerebrospinal fluid

by  /  15 November 2016

Lowering the levels of OTX2, a protein found in the fluid that bathes the brain, prevents many abnormal behaviors in mouse models of Rett syndrome.

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Stem cell transplant makes rats more social

by  /  14 November 2016

Injecting stem cells into young rats makes them more social and flexible when learning tasks than before the treatment.

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July 2016

Neurons from boys with autism grow unusually fast

by  /  28 July 2016

Cells derived from the skin of boys and men with autism share a host of unusual characteristics.

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Two types of neurons play key roles in Rett syndrome

by  /  27 July 2016

Manipulating MeCP2, the gene mutated in Rett syndrome, has revealed two neuron types as crucial contributors to the condition.

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