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Spectrum: Autism Research News

Tag: SCN2A

March 2021
Oligodendrocyte shown orange on black in this scanning electron micrograph.

How oligodendrocytes may shape autism

by  /  15 March 2021

A growing body of evidence shows that brain cells called oligodendrocytes may play a larger role in autism than previously thought.

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February 2021
Oligodendrocyte gene grouping showing network of blue lines connecting the gene names on reddish bubbles.

Differing gene functions across species may pose problems for autism models

by  /  22 February 2021

Misaligned gene expression maps suggest that some autism-linked genes play distinct roles in mouse and human brains.

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Mutations in frogs point to autism genes’ shared role in neurogenesis

by  /  10 February 2021

Mutations in any of 10 autism-linked genes in frogs lead to the same overabundance of brain cells that develop into neurons; the sex hormone estrogen lowers this excess.

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December 2019

Five hot topics in autism research in 2019

by  /  23 December 2019

This year’s hot topics in autism research center around brain organoids, heart rate, the gut microbiome, treatment timing and early detection.

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October 2019
a human brain model made of springs is shaking on its spring base

The link between epilepsy and autism, explained

by  /  21 October 2019

Autism and epileptic seizures often go hand in hand. What explains the overlap, and what does it reveal about autism’s origins?

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CRISPR therapy may reverse autism mutation’s effects well past infancy

by  /  20 October 2019

Injecting the gene-editing tool CRISPR into the brains of mice may reverse the effects of an autism mutation at any age.

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June 2019
children standing in a line, oldest to youngest

Timing of autism treatments may be key to their success

by  /  20 June 2019

The timing of treatment is crucial for conditions related to autism — and more so for some conditions than for others.

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April 2019
children playing at a genetic family group meeting

How families are driving the study of autism genes

by  /  10 April 2019

Parents of children with rare autism-linked mutations are banding together for support and to join forces with scientists, accelerating the pace of research.

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November 2018

Mutations in autism gene may be treatable beyond infancy

by  /  4 November 2018

A top autism gene called SCN2A plays a role at neuronal connections into adulthood, offering hope for treating mutations after infancy.

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April 2018
child with brain scan test

Top autism gene may alter sensory perception

by  /  16 April 2018

An unusual brain response to sound may distinguish children with mutations in SCN2A, a leading candidate gene for autism.

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