A single dose of cannabidiol, a component of marijuana, eases seizures and improves learning and sociability in mice with mutations in an autism gene called CDKL5.

Studies of Rett syndrome hint at genes, cells and brain circuits that may be involved in autism — and may pave the way to treatments for both conditions.

Heart-rate patterns and changes in pupil size may herald Rett syndrome, autism or related conditions.

An experimental leukemia drug and a chemical in black pepper ease breathing and movement problems in a mouse model of Rett syndrome.

Problems with protein-filled parcels called exosomes may contribute to Rett syndrome, a condition related to autism.

Alysson Muotri aims to build a ‘thinking’ brain as a model for autism — even if his colleagues consider that work controversial.

Brain tissues from people with autism of unknown cause and from people with either of two genetic forms of the condition all show similar patterns of methyl groups on DNA.

A new technique may reveal how mutations on the X chromosome alter various types of cells in the brain.

Nearly one in four men who have a daughter with Rett syndrome carry mutations linked to the condition in some of their sperm.

Stimulating the vagus nerve may normalize the brain response to sound in a rat model of Rett syndrome. It may also improve rats’ behavioral response to certain speech sounds.