Tag: Purkinje cells

December 2017

Study of cerebellum’s role in autism homes in on ‘social’ region

by  /  18 December 2017

New evidence from both people and mice points to a part of the cerebellum that helps process social information as being critical in autism.

1 Comment
February 2015
News / Toolbox

Timed cues create mini-cerebellum in culture

by  /  25 February 2015

Researchers can coax human stem cells to grow into layered structures that mimic the brain’s center for motor control, the cerebellum.

January 2015

Autism gene acts as ‘switch’ for brain development genes

by  /  8 January 2015

The autism-linked gene AUTS2 activates a group of genes that may be important for early brain development. The findings, published 18 December in Nature, hint at AUTS2’s potential role in autism and other developmental disorders.


Surplus of synapses may stunt motor skills in autism

by  /  5 January 2015

An overabundance of neuronal connections in the brains of people with autism may contribute to the motor impairments associated with the disorder.

November 2014

Treatment prevents autism-like symptoms in ‘teenage’ mice

by  /  16 November 2014

A treatment that targets the genetic defect in tuberous sclerosis prevents autism-like symptoms in mice at 6 weeks of age — the mouse equivalent of adolescence. Researchers presented the unpublished results yesterday at the 2014 Society for Neuroscience annual meeting in Washington, D.C.

1 Comment
April 2014
Opinion / Viewpoint

The cerebellum’s surprisingly evolved role in autism

by  /  1 April 2014

Thought until recently to only coordinate motor skills, the cerebellum is involved in diverse cognitive functions such as language and social interaction, and may play a role in autism, says Emanuel DiCicco-Bloom.

January 2014

Mounting evidence implicates cerebellum in autism

by  /  6 January 2014

Results from four studies published in the past year point to a role for the cerebellum in autism-related behaviors.

January 2013

Study fingers cause of motor problems in Angelman syndrome

by  /  28 January 2013

A net decrease in inhibitory signals in the cerebellum may underlie the movement problems seen in the autism-related disorder Angelman syndrome, according to mouse research published 5 December in Science Translational Medicine.

October 2012
News / Toolbox

New technique takes sharp look at whole mouse brains

by  /  17 October 2012

A new microscopy technique allows researchers to take high-resolution three-dimensional images of intact mouse brains.


Autism mouse models show glitch in motor learning

by  /  16 October 2012

Two well-known mouse models of autism show abnormal reactions to an eye-blinking test that relies on the cerebellum, a brain region that helps integrate sensory information and plan movements. The unpublished results were presented in a poster Monday at the 2012 Society for Neuroscience annual meeting in New Orleans.

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