Tag: Purkinje cells

February 2015
News / Toolbox

Timed cues create mini-cerebellum in culture

by  /  25 February 2015

Researchers can coax human stem cells to grow into layered structures that mimic the brain’s center for motor control, the cerebellum.

0 Comments
January 2015
News

Autism gene acts as ‘switch’ for brain development genes

by  /  8 January 2015

The autism-linked gene AUTS2 activates a group of genes that may be important for early brain development. The findings, published 18 December in Nature, hint at AUTS2’s potential role in autism and other developmental disorders.

2 Comments
News

Surplus of synapses may stunt motor skills in autism

by  /  5 January 2015

An overabundance of neuronal connections in the brains of people with autism may contribute to the motor impairments associated with the disorder.
 

5 Comments
November 2014
News

Treatment prevents autism-like symptoms in ‘teenage’ mice

by  /  16 November 2014

A treatment that targets the genetic defect in tuberous sclerosis prevents autism-like symptoms in mice at 6 weeks of age — the mouse equivalent of adolescence. Researchers presented the unpublished results yesterday at the 2014 Society for Neuroscience annual meeting in Washington, D.C.
 

1 Comment
April 2014
Opinion / Viewpoint

The cerebellum’s surprisingly evolved role in autism

by  /  1 April 2014

Thought until recently to only coordinate motor skills, the cerebellum is involved in diverse cognitive functions such as language and social interaction, and may play a role in autism, says Emanuel DiCicco-Bloom.

11 Comments
January 2014
News

Mounting evidence implicates cerebellum in autism

by  /  6 January 2014

Results from four studies published in the past year point to a role for the cerebellum in autism-related behaviors.

8 Comments
January 2013
News

Study fingers cause of motor problems in Angelman syndrome

by  /  28 January 2013

A net decrease in inhibitory signals in the cerebellum may underlie the movement problems seen in the autism-related disorder Angelman syndrome, according to mouse research published 5 December in Science Translational Medicine.

0 Comments
October 2012
News / Toolbox

New technique takes sharp look at whole mouse brains

by  /  17 October 2012

A new microscopy technique allows researchers to take high-resolution three-dimensional images of intact mouse brains.

0 Comments
News

Autism mouse models show glitch in motor learning

by  /  16 October 2012

Two well-known mouse models of autism show abnormal reactions to an eye-blinking test that relies on the cerebellum, a brain region that helps integrate sensory information and plan movements. The unpublished results were presented in a poster Monday at the 2012 Society for Neuroscience annual meeting in New Orleans.

1 Comment
July 2012
News

Tuberous sclerosis gene loss triggers autism-like features

by  /  26 July 2012

Losing one or both copies of TSC1, one of the two genes responsible for tuberous sclerosis complex, in specific cells of the cerebellum can trigger several autism-like behaviors in mice, according to research published 1 July in Nature.

1 Comment
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