Maternal genetics may contribute to autism-like traits in mice via inflammation
A mouse model hints that genes linked to inflammation in some women may increase the likelihood of autism in their children.
A mouse model hints that genes linked to inflammation in some women may increase the likelihood of autism in their children.
A genetic therapy and an existing drug both restore typical brain size in mice missing DYRK1A, a top autism candidate gene, in the cerebral cortex, a new study shows. The animals typically have smaller brains than controls.
A growing body of evidence shows that brain cells called oligodendrocytes may play a larger role in autism than previously thought.
Blood levels of PTEN protein and associated molecules could eventually help diagnose autism and other neurological conditions — and predict their outcomes.
A new tool enables researchers to create mosaic mutations in only some cells and then accurately identify which cells are affected.
Mice missing a copy of the autism-linked gene PTEN show a reduced preference for social interaction, possibly due to atypically large, overconnected dopamine neurons. Easing the overconnection may alleviate this trait.
A new analysis links individual mutations in a gene called PTEN to a person’s odds of having autism, cancer or other conditions.
The overproduction of proteins in brain cells called microglia causes social impairments, cognitive deficits and repetitive behavior in male mice, a new study has found.
Lowering the levels of a protein called tau, best known for its involvement in Alzheimer’s disease, improves behavior in two mouse models of autism.
Deletions and duplications of long stretches of DNA may increase the likelihood of autism in people who have a mutation in a gene called PTEN.