Therapies that target the circuit could boost social activity, new findings suggest.

Ramping up levels of one isoform of the autism-linked protein reverses traits in model mice, a new study shows.

Together, the neurons are part of the corticostriatal circuit, which has been implicated in autism.

The open-source device achieves subcellular resolution in a larger tissue volume than was possible with prior miniscopes, without impinging upon a mouse’s behavior.

The animals recall fear more readily if a set of inhibitory neurons in the hippocampus is switched on.

The calcium-sensing instrument translates neuronal activity into signals that can be detected via functional magnetic resonance imaging (fMRI).

A 3D optogenetics method can mimic natural rhythms of neural activity, rendering previously unanswerable questions amenable to inquiry — including questions about autism.

The new method, called sonogenetics, noninvasively manipulates neural circuits in mice.

Sleep problems may contribute to or derive from autism traits — or both. After decades of work, researchers are beginning to uncover the biological connections between the two conditions, revealing new paths to potential treatments.

Mice missing a copy of the gene SENP1 have atypical social behavior likely due to a signaling imbalance in the retrosplenial cortex.