Molecular signature may lead to blood test for autism
Researchers have identified a distinctive pattern of gene expression in the white blood cells of young autistic boys.
Researchers have identified a distinctive pattern of gene expression in the white blood cells of young autistic boys.
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Analyzing gene expression in a vision center of the mouse brain has revealed 49 different classes of cells.
A mathematical model of the brain’s circuits shows how neurons stuck in overdrive could produce symptoms of autism. The model may reveal how autism-linked behaviors arise from underlying biology.
Researchers have for the first time mapped gene expression in the rhesus macaque brain from birth through adulthood. The atlas illuminates the expression patterns of genes likely to be important in autism.
A cluster of neurons helps monkeys cooperate, and a human gene makes a mouse brain look like a person’s.
The little-studied autism gene ANKRD11 helps to package DNA in the nucleus and plays a critical role in the early growth and positioning of neurons.
Mice with mutations in the autism-linked gene WDFY3 have enlarged brains reminiscent of those seen in some children with autism, according to a study published 8 September in Nature Communications.
FMRP, the protein absent or mutated in fragile X syndrome, aids in strategic elimination of neuronal connections during brain development in mice, according to a study published 26 February in The Journal of Neuroscience.
Two new maps of the brain — an atlas of fetal development and a wiring diagram in the mouse — debuted 2 April in Nature. The maps may open new avenues of investigation into the genetic and neurological basis of autism.