Tag: mouse models

October 2016
Doctor Jason Lerch and Doctor Jacob Ellegood are photographed in their Toronto lab on October 14, 2016. JENNIFER ROBERTS
News / Profiles

Meet the dynamic duo scanning every autism mouse brain

by  /  24 October 2016

At the Mouse Imaging Centre in Toronto, Jacob Ellegood and Jason Lerch are taking on autism’s complexity by scanning the brain of every autism mouse model they can acquire.

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News

Autism gene needed for growth of neurons during gestation

by  /  7 October 2016

Mutations in one of the strongest autism candidate genes may block the proliferation of neurons during development.

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Opinion / Q&A

Questions for Rudolf Jaenisch: Creating mouse-human hybrids

by  /  4 October 2016

Despite ethical concerns, watching how human neurons develop in the mouse brain could help scientists understand conditions such as autism.

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September 2016
Opinion / Q&A

Questions for Rafael Yuste: How to rewire neurons with light

by  /  27 September 2016

Repeatedly activating a group of neurons causes them to fire as a unit on their own. Once the ensemble has formed, stimulating a single neuron triggers activity in the rest of the group.

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News

Mice with faulty SHANK3 mimic autism features in people

by  /  26 September 2016

Mice with a genetic glitch in just one copy of SHANK3, a leading candidate gene for autism, show brain and behavioral features of the condition.

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News

Brain’s immune cells may only play bit part in Rett syndrome

by  /  21 September 2016

Contrary to some previous reports, microglia may not play a central role in initiating Rett syndrome.

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News

Loss, doubling of Rett gene produce similar brain glitch

by  /  15 September 2016

Mice with either too little or too much MeCP2, the gene mutated in Rett syndrome, show similar malfunctions in a learning and memory circuit.

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News

Mice missing top autism gene make their debut

by  /  12 September 2016

Mice lacking one copy of CHD8, a key autism gene, show signs of social deficits and broad changes in gene expression.

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August 2016
News

Motor troubles in Angelman may stem from nerve fiber anomaly

by  /  1 August 2016

Unusually thin nerve fibers in the brain may underlie the motor difficulties seen in children with Angelman syndrome, an autism-related condition.

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July 2016
News

Neurons from boys with autism grow unusually fast

by  /  28 July 2016

Cells derived from the skin of boys and men with autism share a host of unusual characteristics.

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