Too many or too few copies of a segment of chromosome 16 alters the three-dimensional organization of DNA, and affects hundreds of related genes.

Mini-brains grown from stem cells in culture can reveal the effects of both autism and the Zika virus on early development.

Mutations in a gene called POGZ lead to a constellation of traits, including a small head, developmental delay and, often, autism.

Researchers are building on the bright ideas of high school students to bring ambitious biotechnology tools to life.

The first in-depth look at people with alterations in the 1q21.1 chromosomal region reveals a range of features, from problems with fine motor skills to autism.

Missing a swath of chromosome 16 with strong ties to autism disrupts proteins crucial for early brain development. The findings open the door to targeted interventions.

Mutations in the gene DYRK1A underlie a type of autism marked by an unusually small head. The new work expands the breadth of symptoms included under the autism umbrella.

The little-studied autism gene ANKRD11 helps to package DNA in the nucleus and plays a critical role in the early growth and positioning of neurons.

Deletion or duplication of 16p11.2, a chromosomal region linked to autism, may trigger symptoms via the interactions of genes both within and outside the region at a key point in development. Researchers presented these preliminary results Sunday at the 2014 American Society of Human Genetics Annual Meeting in San Diego.

Having an enlarged head in early childhood is not a reliable marker of autism, according to two new studies that tracked changes in head and body size in children over time.