Tag: MECP2

November 2017
Features / Webinars

Journal club: Exploring treatments for Rett syndrome

11 December 2017

Register for the next Spectrum journal club, which will feature two papers about therapies that adjust levels of the Rett syndrome protein MECP2.

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News

Experimental Huntington’s drug improves gait in Rett mice

by  /  14 November 2017

A candidate drug in clinical trials for Huntington’s disease reverses gait problems in a mouse model of Rett syndrome.

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News

Rett syndrome mutation’s effects vary by cell type

by  /  14 November 2017

Mutations in the Rett syndrome gene MECP2 have different effects on subtypes of neurons.

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News

Scientists move closer to gene therapy for Rett syndrome

by  /  14 November 2017

A virus that delivers a working copy of the Rett syndrome gene to the brain improves features of the condition in mice, and appears to be safe in monkeys.

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News

Soothing sensory sensitivity may ease social problems in mice

by  /  12 November 2017

A treatment delivered to neurons that mediate touch can ease anxiety and social problems in two mouse models of autism.

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October 2017
News

‘Mini-gene’ therapy relieves features of Rett syndrome in mice

by  /  11 October 2017

Delivering a fragment of the Rett syndrome gene MECP2 into neurons eases features of the syndrome in a mouse model.

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News

Two drugs ease features of autism syndromes in mice

by  /  11 October 2017

Drugs that block certain brain enzymes could help treat two conditions associated with autism.

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September 2017
News

Rat study ties Rett syndrome gene to pain processing

by  /  21 September 2017

Mutations in MECP2, the gene mutated in Rett syndrome, may alter the proportions and activity of sensory neurons in rats.

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June 2017
Opinion / Viewpoint

Family groups play key role in advancing autism research

by  /  27 June 2017

Families need more support from researchers in order for their heroic efforts to be optimally effective.

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News

Mutant monkeys mimic features of autism, Rett syndrome

by  /  19 June 2017

Monkeys with a mutation in the Rett syndrome gene, MeCP2, have social difficulties and repetitive behaviors.

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