Many tests for unusual behavior in mice are prone to operator error. Here’s how to avoid common traps.
A maze comprising 37 hexagonal platforms may offer researchers an accurate measure of rodents’ ability to navigate their surroundings.
Using a new task to test resistance to change in autism, we are developing leads for treatments for this troublesome trait.
The same processes that enable the brain to store new memories may also control many autism genes.
Adults with autism who undergo a therapy designed to bolster social learning show cognitive benefits that may increase their chances of employment.
The drug rapamycin, which is in clinical trials as a treatment for tuberous sclerosis, may exacerbate features of fragile X syndrome, another condition related to autism.
A widely used treatment for anxiety can eliminate some of the cognitive and social problems seen in mice missing a copy of ARID1B, a gene associated with autism.
We asked three distinguished autism researchers to reflect on their first studies in the field.
Measures of adaptive functioning may better assess the ability of autistic people to meet daily demands than do intelligence tests.
Male mice with a genetic variant tied to autism may have learning difficulties that females with the variant do not.
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