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Spectrum: Autism Research News

Tag: interneurons

March 2013

Molecular mechanisms: Deletion moves inhibitory neurons

by  /  1 March 2013

Loss of one copy of 22q11.2 — a chromosomal region linked to schizophrenia and autism — shifts the location of neurons that inhibit brain signals, according to a study published 6 November in Proceedings of the National Academy of Sciences.

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November 2012

Molecular mechanisms: Autism gene regulates brain structure

by  /  30 November 2012

Loss of one copy of TBR1, an autism-linked gene involved in fetal brain development, leads to brain malformations, according to a study published in the September issue of Molecular Syndromology.

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Insights for autism from schizophrenia

by ,  /  13 November 2012

Lessons learned from postmortem studies of schizophrenia are applicable to research on autism, a disorder for which brain tissue has not been as well studied, say Allison Curley and David Lewis.

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September 2012
Illustration of a brain neuron.

Device helps record neuronal activity in moving rats

by  /  5 September 2012

A new device allows researchers to identify the precise source of an emitted brain signal measured in freely moving rats, according to a study published in the July issue of the Journal of Neurophysiology.

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August 2012
Brain waves against a solid white background

Epilepsy drug reverses autism-like symptoms in mice

by  /  27 August 2012

Researchers have homed in on the brain region thought to be responsible for the autism-like symptoms that can accompany Dravet syndrome, a rare epilepsy disorder, according to research published Wednesday in Nature.

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July 2012

Angelman mice show impaired inhibition of brain signals

by  /  2 July 2012

Mice lacking a functional copy of UBE3A, the gene missing or mutated in people with the rare developmental disorder Angelman syndrome, show less inhibitory activity than controls do, according to research published 7 June in Neuron.

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June 2012

Molecular mechanisms: Language neurons small in autism

by  /  13 June 2012

Neurons that activate signals in a brain region important for language and imitation are smaller in the brains of individuals with autism than in those of controls, according to a study published 31 March in Acta Neuropathology.

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January 2012

New technique charts patterns of microRNA expression

by  /  25 January 2012

Researchers have mapped the levels of tiny RNA fragments that regulate gene expression in specific brain regions and subtypes of neurons. The results were published 12 January in Neuron.  

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November 2011

Mouse models point to early troubles in tuberous sclerosis

by  /  28 November 2011

The brain abnormalities characteristic of tuberous sclerosis may begin early in development and involve malfunctioning of neuronal precursors, according to studies of two different mouse models of the disorder published in October.

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A case for the importance of interneurons in autism

by ,  /  22 November 2011

The etiology of autism may be best understood as an impairment of neuronal circuits, specifically interneurons that dampen signals in the brain, says neuroscientist Gordon Fishell.  

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