Autism-related genes converge on microglia and dopamine in zebrafish
The findings add to the growing evidence that genes with disparate functions can play similar roles in brain development.
The findings add to the growing evidence that genes with disparate functions can play similar roles in brain development.
Genes exert their strongest influence on the brain in the first half of gestation — a key window for autism and other neurodevelopmental conditions.
The gene, FOXP1, influences an animal’s motivation to listen to social communication, a new study suggests.
The changes may help explain the link between maternal infection and autism, though more research is needed.
A machine-learning technique applied to brain imaging data appears to predict a person’s mix of verbal intelligence, social affect and repetitive behaviors.
The proteins are part of a newly discovered complex that mends genetic damage exclusively in neurons.
Both human and mouse progenitor cells with the alterations struggle to become neurons and instead express genes that are typically active only in muscle or the heart.
The treatment eases the animals’ sleep troubles, suggesting it has clinically meaningful effects beyond what was thought to be a critical window in early life.
Five autism-linked genes widely known as chromatin regulators appear to also shape the cell’s internal skeleton.
Exposing neurons to valproic acid, a well-known environmental risk factor for autism, disrupts their ability to generate different proteins from the same gene.