Tag: gene expression

November 2017
Features / Webinars

Journal club: Exploring treatments for Rett syndrome

11 December 2017

Register for the next Spectrum journal club, which will feature two papers about therapies that adjust levels of the Rett syndrome protein MECP2.

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News / Toolbox

New technique ramps up editing of genes in stem cells

by  /  17 November 2017

A novel method allows researchers to rapidly generate stem-cell colonies with mutations linked to autism or other conditions.

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News

Map of microglia in mouse brain may reveal role in autism

by  /  15 November 2017

Researchers have mapped how immune cells in the brain called microglia change with age in mice.

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News

Maternal asthma alters immune cells in fetal brain

by  /  14 November 2017

Mouse pups exposed to an immune response in the womb show autism-like behaviors and altered gene expression in brain cells called microglia.

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News

Rett syndrome mutation’s effects vary by cell type

by  /  14 November 2017

Mutations in the Rett syndrome gene MECP2 have different effects on subtypes of neurons.

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News

‘Mini-brains’ mirror fetal brain development

by  /  14 November 2017

Spheres of brain cells derived from a fetal skull have gene expression patterns similar to those in brain tissue from the same fetus.

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News

Autism may disrupt the body’s circadian clock

by  /  13 November 2017

Sleep problems in autism may stem from the same biological changes that underlie the core features of the condition.

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News

Brain cells spun from skin point to subtypes of autism

by  /  12 November 2017

Neurons derived from people with a syndromic form of autism look and behave differently than do those from people with classic autism.

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News

Distinct set of genes controls brain activity in people with autism

by  /  12 November 2017

A different set of genes regulates brain activity in people with autism than the set involved in controls.

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Features / Deep Dive

Banking on brains for clues to autism

by  /  1 November 2017

New initiatives aim to increase brain donations for autism research and maximize what scientists can learn from these precious specimens.

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