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Spectrum: Autism Research News

Tag: GABA

November 2017
Mice that lack UBE3A only in their inhibitory neurons are particularly susceptible to seizures.

Gene therapy technique prevents seizures in Angelman mice

by  /  12 November 2017

Introducing the gene UBE3A into neurons that dampen brain activity prevents seizures in a mouse model of Angelman syndrome.

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October 2017
Microscope image of neuronal injections in brain.

Two drugs ease features of autism syndromes in mice

by  /  11 October 2017

Drugs that block certain brain enzymes could help treat two conditions associated with autism.

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August 2017
Week of AugustAug
7th
2017

Off-key outcomes; visualizing variants; urine indifference and more

by  /  11 August 2017

Music therapy proves ineffective for autism, brain structures differ with 16p11.2 duplications and deletions, and mice missing NLGN3 may influence the sociability of their littermates.

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Flash of light shifts social behavior in autism mice

by  /  2 August 2017

Turning on a set of neurons that dampen brain activity improves social behavior in a mouse model of autism; turning off neurons that excite brain activity does the same thing.

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July 2017

Drug that shifts brain’s signaling balance could treat autism

by  /  20 July 2017

A drug that alters the balance of two key chemical messengers in the brain may help treat autism, suggests a proof-of-principle study.

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May 2017

Hallucinations unusually common in adults with autism

by ,  /  24 May 2017

Negative experiences, such as being bullied or socially isolated, may lead to hallucinations.

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Altered circuit may underlie repetitive behaviors in autism

by  /  13 May 2017

A brain circuit that controls movement is altered in people with autism, a postmortem brain study suggests.

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March 2017

In trials, repurposed drug shows promise for autism

by  /  27 March 2017

A drug used to treat excessive swelling seems to ease autism features in some children on the spectrum.

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Questions for Huda Zoghbi: Studying Rett in the rodent brain

by  /  14 March 2017

Removing the Rett syndrome gene, MeCP2, from distinct cells and brain regions reveals hidden features of the condition.

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January 2017

Sound processing skewed in mouse model of Rett syndrome

by  /  27 January 2017

Researchers have traced an unusual maternal behavior in female mice modeling Rett syndrome to a neural circuit that processes sound. They have also found a drug that reverses this behavior.

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