Contrary to previous results, the blood pressure drug did not uniformly improve autism traits in a new clinical trial.

Mice missing an autism gene called SHANK3 tend to be hypersensitive to touch, which may stem from underactivity of neurons that normally dampen sensory responses.

Autism and epileptic seizures often go hand in hand. What explains the overlap, and what does it reveal about autism’s origins?

Studies of Rett syndrome hint at genes, cells and brain circuits that may be involved in autism — and may pave the way to treatments for both conditions.

Deleting an autism gene called TRIO derails neurons’ journey to their destination.

An experimental drug that muffles the activity of neurons in the skin moderates heightened reactions to touch in six mouse models of autism.

Mutations in the autism gene NLGN3 may alter the gut nervous system of mice.

Mice colonized with gut microbes from some autistic boys show behaviors like those of the boys.

The signaling imbalance theory holds that the brains of autistic people are hyper-excitable because of either excess neuronal activity or weak brakes on that activity.

The brains of rats exposed in utero to the seizure drug valproate show a significant increase in brain size around the time of birth.