A new approach for delivering gene therapy to the brain reduces nerve damage in primates and could help make gene therapies for conditions related to autism safer.

A Hollywood-inspired video tool that captures movement in three dimensions over extended time periods shows that rats lacking the autism-linked gene FMR1 have different grooming patterns than controls do.

On 10 February, André Fenton spoke about rethinking dysfunction in fragile X model mice.

Sensory problems in people with fragile X syndrome may stem from hyperactive neurons, a mouse model study suggests.

Gene therapies and the factors influencing autism traits top Spectrum’s list of the 10 most notable research findings we covered in 2020.

Get the inside scoop from the 2020 American Society of Human Genetics annual meeting.

People with particularly low levels of FMRP, the protein lacking in those with fragile X syndrome, are more likely to also have autism and severe intellectual disability.

A gene therapy for Angelman syndrome stands at the forefront of efforts to treat autism-linked conditions that stem from single genes.

Plugging a leaky mitochondrial membrane may help fragile X neurons to mature and function more efficiently.

Autistic people and their families are increasingly experimenting with marijuana to try to ease problems such as insomnia, epilepsy and chronic pain — and traits of autism. But there is little evidence for its safety or effectiveness.