Tag: fragile X syndrome

January 2018
Week of JanuaryJan
15th
2018
News / Spotted

Social genome; nonspeaking host; microbiome brain and more

by  /  19 January 2018

Common genetics may help forge social ties, a nonspeaking woman with autism hosts “The Late Show,” and the mix of bacteria in the gut may relate to brain structure.

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November 2017
News

Learning shows sex bias in mice with mutation tied to autism

by  /  23 November 2017

Male mice with a genetic variant tied to autism may have learning difficulties that females with the variant do not.

1 Comment
Week of NovemberNov
13th
2017
News / Spotted

Adult assessment; fragile therapy; neuron nirvana and more

by  /  17 November 2017

An interview for diagnosing adults on the spectrum clears its first hurdle, a fragile X drug eases multiple features of the syndrome in a mouse model, and a brain bank chronicles the beautiful diversity of neurons.

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News

Mouse imaging study hints at how fragile X drug trial went wrong

by  /  15 November 2017

The drug mavoglurant has no effect on a brain circuit involved in social behavior in a mouse model of fragile X syndrome. That may explain its poor performance in people with the condition.

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News

Selective enzyme block reveals new treatment for fragile X

by  /  14 November 2017

A drug that selectively blocks one form of an enzyme called GSK-3 prevents seizures and improves cognitive deficits in a mouse model of fragile X syndrome.

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News

Magnetic stimulation bares imbalance of activity in fragile X brains

by  /  14 November 2017

Researchers have used transcranial magnetic stimulation to show that people with fragile X syndrome have weak ‘inhibitory’ signals, those that dampen neuronal activity in the brain.

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News

Autism may disrupt the body’s circadian clock

by  /  13 November 2017

Sleep problems in autism may stem from the same biological changes that underlie the core features of the condition.

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News

‘Fragile’ behaviors mar studies of popular autism mouse model

by  /  13 November 2017

Researchers should proceed with caution when studying the behavior of one of the most popular mouse models of autism: the fragile X mouse model.

1 Comment
News

Fragile X behaviors may stem from gene’s loss in specific cells

by  /  13 November 2017

Deleting FMR1, the gene mutated in fragile X syndrome, in subsets of mouse neurons leads to distinct features of the condition.

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News

Three autism mouse models marked by defects in same circuit

by  /  8 November 2017

Problems with social interactions stem from faulty wiring of a single circuit spanning distant brain regions, results from three mouse models of autism suggest.

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