Tag: FMRP

September 2017
Opinion / Viewpoint

Protein factories at neuronal junctions take center stage in autism

by ,  /  12 September 2017

Some genes linked to autism regulate the production of proteins at neuronal junctions, suggesting that disrupted protein synthesis contributes to the condition.

0 Comments
March 2017
illustration of person with autism struggling with addiction
Features / Deep Dive

Autism’s hidden habit

by  /  1 March 2017

Conventional wisdom holds that people with autism don’t get hooked on alcohol or other drugs, but new evidence suggests otherwise.

4 Comments
February 2017
Features / Deep Dive

Why don’t we have better drugs for autism?

by  /  15 February 2017

Clinical trials for autism drugs have been plagued with problems: bad design, the wrong measures, too broad a range of participants. All that is finally starting to change.

1 Comment
November 2016
News

Despite setbacks, fragile X drugs file into clinical trials

by  /  30 November 2016

Our infographic displays efforts to develop treatments for fragile X syndrome. So far, none of them have passed muster in clinical trials.

0 Comments
September 2016
News / Toolbox

Glowing cells bolster search for fragile X drugs

by  /  2 September 2016

A new genetic trick allows researchers to quickly spot the most promising treatments for fragile X syndrome among thousands of candidate compounds.

0 Comments
July 2016
News / Toolbox

Gene-editing tool locates proteins inside brain cells

by  /  8 July 2016

The popular gene-editing tool CRISPR can tag proteins in the brain, illuminating the whereabouts of autism candidates.

0 Comments
May 2016
News

Experimental cancer drug restores memory in fragile X mice

by  /  26 May 2016

An early-stage treatment for eye cancer reverses memory problems in a mouse model of fragile X syndrome.

0 Comments
March 2016
Features / Webinars

Webinar: Claudia Bagni details molecular pathways in fragile X syndrome

23 March 2016

Watch the replay of Claudia Bagni’s webinar, in which she described molecular pathways that are impaired in fragile X syndrome, autism and schizophrenia. She also discussed mouse and fly models, as well as human cells.

1 Comment
October 2015
News

Genetic fix for star-shaped cells eases fragile X in mice

by  /  20 October 2015

Boosting levels of the fragile X protein FMRP in astrocytes reverses features of fragile X syndrome in mice.

0 Comments
News

New methods tighten ​net​ around autism genes

by  /  9 October 2015

Autism researchers are sharpening their statistical tools to make sense of the growing pool of autism genes.

0 Comments
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