The in-depth approach shows mutations in the autism-linked gene disrupt neuronal growth and communication, as well as mitochondrial gene expression.

The circuit linking the prefrontal cortex and part of the thalamus is impaired in mice raised in social isolation and in mice with mutations in the FMR1 or TSC2 genes.

Iama Therapeutics is hoping a new class of molecule will prove successful against an old target in autism.

The drug quells seizures in children with Dravet syndrome or Lennox-Gastaut syndrome.

Long cast in supporting roles in the brain, astrocytes are now emerging as primary players in certain characteristics of autism and related conditions.

The catalog could help researchers understand the effects of autism-linked DNA variants that fall outside genes.

Therapies that target the circuit could boost social activity, new findings suggest.

Neurons with a faulty copy of SETD1A, a gene tied to autism and schizophrenia, show structural abnormalities and altered connectivity patterns.

The experimental compound, called GSK-LSD1, enhances social preferences and reduces repetitive grooming in mice, according to a new study.

The animals recall fear more readily if a set of inhibitory neurons in the hippocampus is switched on.