Vast diversity of human brain cell types revealed in trove of new datasets
The collection offers a glimpse into differences in cell composition — across people and brain regions — that may shape neural function.
The collection offers a glimpse into differences in cell composition — across people and brain regions — that may shape neural function.
Alterations in inhibitory circuits and difficulties in social recognition characterize mice missing one copy of DYRK1A, a gene linked to autism.
An imbalance in the number of excitatory neurons in early brain development may account for the difference.
Synaptic changes in the brain region could drive a core trait of fragile X syndrome, a new mouse study suggests.
A protective pathway that pauses protein synthesis is muted in a mouse model of fragile X syndrome, according to a new study.
A subset of thalamic neurons support an aspect of social behavior called social recognition, according to experiments in mice.
Autistic children taking the drug showed improvements in some behaviors but not in their social skills.
Cannabidiol (CBD) blocks the action of a molecule that drives an overexcitability feedback loop in a rodent model of epilepsy.
Conventional optogenetic manipulations to excite or inhibit neurons stop when the light switches off. A new approach makes the changes last.
A new gene therapy approach for epilepsy tamps down neural activity on demand.