A new imaging technique that can assemble finely detailed pictures of an individual mouse’s brain in less than a day is being used to explore mouse models of autism. Data from the first two models were presented Wednesday at the 2013 Society for Neuroscience annual meeting in San Diego.
Rett syndrome affects many cellular pathways, but correcting just one of these with drugs approved for other purposes may be enough to alleviate symptoms of the disorder. This was the message from two presentations Tuesday at the 2013 Society for Neuroscience annual meeting in San Diego.
Two studies in autism rat models suggest that a high-fat, low-carbohydrate diet and an unapproved drug for dementia may improve some symptoms of the disorder, according to unpublished results presented Sunday at the 2013 Society for Neuroscience annual meeting in San Diego.
Researchers have recreated one of the most popular rodent models of autism in a decidedly slimier animal: the tadpole. The unpublished study was presented Sunday at the 2013 Society for Neuroscience annual meeting in San Diego.
The largest genetic analysis yet conducted of people lacking a brain structure called the corpus callosum shows that the condition shares many risk factors with autism. The study was published 3 October in PLoS Genetics.
Researchers have mined the medical records of more than 100 million people and found close to 3,000 associations between single-gene diseases, such as cystic fibrosis, and complex genetic disorders such as autism. The results were published 26 September in Cell.
A new candidate gene for autism, called synapsin 2, regulates chemical messenger release across the connections between neurons, reports a study published 4 September in Human Molecular Genetics.
Mutations in GABRB3, a brain receptor linked to autism, are prevalent in severe childhood epilepsy, according to a study published 12 September in Nature.
Elliott Sherr is unraveling the effects of genetics and brain structure in a handful of disparate disorders that each illuminates some aspect of autism.
Clinicians should place children under age 5 who have developmental delay into a broad diagnostic category, called ESSENCE, which may then resolve into any number of individual diagnoses over time, says Christopher Gillberg.