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Spectrum: Autism Research News

Tag: connectivity theory

June 2022
A computer-rendered analysis of neurons

Autism-linked mutation disrupts brain circuit to change social behavior

by  /  24 June 2022

Therapies that target the circuit could boost social activity, new findings suggest.

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November 2021

Synaptic overgrowth, hyperconnectivity may define autism subtype

by  /  18 November 2021

Model mice of the subtype also show hyperactivity in a signaling pathway called mTOR, bolstering the idea that distinct forms of autism have different biological roots and may require different treatment approaches.

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October 2021
Black CDKL5 mice in a lab setting--three mice in a cage.

Brain stimulation improves memory in autism mouse models

by  /  15 October 2021

Jolting a bundle of nerve fibers deep in the brain restores learning and memory in mice with mutations of the autism-linked gene CDKL5.

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September 2021
Colorful image of a composite of multiple brain scans showing communication patterns in different regions.

Autism mouse models cluster by brain activity pattern

by  /  10 September 2021

Four subtypes lend new support to the idea that there isn’t a single ‘hallmark’ type of brain connectivity in people with autism.

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May 2021
Neurons in red and green

‘Neurons on a chip’ reveal patterns across autism-linked conditions

by  /  7 May 2021

Activity patterns of neuronal networks link different genetic subtypes of autism that have similar traits, according to new unpublished research.

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November 2020
Brain diagrams showing connectivity within different regions.

Gene mutations point to overlaps in brain connectivity for autism, schizophrenia

by  /  30 November 2020

People who have large mutations associated with autism and schizophrenia share atypical patterns of brain connectivity, according to a new study, especially between areas that process sensory information.

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September 2019

Slow, disorderly brain waves may flag autism in toddlers

by  /  23 September 2019

Certain patterns of electrical activity in the brain may signal autism in children with tuberous sclerosis complex, a related genetic condition.

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June 2019
Mouse neurons in a grid show differences

Autism mutation may disrupt brain structure by disabling mitochondria

by  /  13 June 2019

Mice that lack a segment of chromosome 22 — a mutation associated with autism — have unusually sparse connections between brain regions.

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Illustration of cerebellum in human brain

Communication in brain shows sex difference in autism

by  /  3 June 2019

Autistic women show unusually strong connections, and autistic men unusually weak ones, between two brain regions.

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May 2019
overlapping network of connections in the brain

The connectivity theory of autism, explained

by  /  1 May 2019

A growing body of evidence suggests that autism involves atypical communication between brain regions, but how and where in the brain this plays out is unclear.

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