Vast diversity of human brain cell types revealed in trove of new datasets
The collection offers a glimpse into differences in cell composition — across people and brain regions — that may shape neural function.
The collection offers a glimpse into differences in cell composition — across people and brain regions — that may shape neural function.
Children with congenital heart disease have an increased likelihood of autism. Why?
Many genes related to the condition play a role in the internal scaffolding of cells, and cytoskeletal disruptions can affect neurodevelopment and behavior.
The proteins are part of a newly discovered complex that mends genetic damage exclusively in neurons.
Exposing neurons to valproic acid, a well-known environmental risk factor for autism, disrupts their ability to generate different proteins from the same gene.
A new atlas reveals how the structural shake-ups within a cell’s genome differ by cell type and brain region over time.
What these genes do and how they affect autism depends on when in development they’re studied, despite what classic ‘gene ontology’ analyses say.
The catalog could help researchers understand the effects of autism-linked DNA variants that fall outside genes.
The experimental compound, called GSK-LSD1, enhances social preferences and reduces repetitive grooming in mice, according to a new study.
Mutations in all three accelerate the maturation of inhibitory neurons, which could upset the brain’s balance of excitation and inhibition early in development.