Mutations in any of 10 autism-linked genes in frogs lead to the same overabundance of brain cells that develop into neurons; the sex hormone estrogen lowers this excess.

Many people with mutations in the NCKAP1 gene have autism or autism traits, according to a new study spanning seven countries.

Like so many other events this year, autism’s biggest annual conference — the International Society for Autism Research meeting — was forced to go virtual because of the coronavirus pandemic.

People with mutations in CHD8, a top autism gene, tend to be tall and have large heads.

Mice missing a copy of CHD8, a top autism gene, show a signaling imbalance in their brains — a finding in line with a popular hypothesis about autism’s origins.

Children with autism who carry mutations in the chromosomal region 16p11.2 or the gene CHD8 — two of the leading risk factors for autism — show distinct patterns of chemical tags on their DNA.

Children with mutations either in CHD8 — a top autism gene — or in genes that CHD8 controls share similar characteristics.

A team of researchers is trialing a fast approach to autism drug development: simultaneously testing candidates in people and in mice.

Mice lacking one copy of a leading autism gene have hyperexcitable brains and problems with learning and memory.

The largest autism sequencing study to date implicates 99 genes in the condition — but nearly half have a tighter link to intellectual disability or developmental delay.