Chromatin ...of known syndromes associated with autism and intellectual disability, for example, Wiedemann Steiner syndrome and Coffin-Siris syndrome. Interestingly, people with mutations in these genes often display a complex constellation of...
Dysmorphology ...Timothy syndrome, Cornelia de Lange syndrome and other autism disorders associated with abnormal embryogenesis. Computerized dysmorphology: A recent adjunct to the standard dysmorphology examination is the computerized assessment of the...
Dendritic spines ...signal-to-noise ratio of information transferred within neuronal circuits. Tissue from people with autism and fragile X syndrome seem to have unusually high spines densities, presumably due to a failure of...
Theory of mind ...In 1985, Baron-Cohen, Frith and Alan Leslie reported that children with autism systematically fail the false-belief test. Children with Down syndrome pass the test, despite having lower intelligence quotients than...
SHANK3 ...been implicated in autism. SHANK3 is located in the 22q13 chromosomal region, which is deleted in individuals with Phelan-McDermid syndrome, a disorder characterized by severe intellectual disability and delayed speech,...
16p ...16p11.2 have also been linked to other conditions such as schizophrenia 7, mental retardation 8, intellectual disability not diagnosed as fragile X, and other known syndromes 9. Individuals who have...