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Emerging tools and techniques that may advance autism research.

Spatial scan: A new method labels thousands of neurons in a fraction of the time traditional approaches take.

Barcode trick traces paths of thousands of neurons in brain

by  /  30 September 2016

A new method labels neurons with barcodes to deduce their routes through the brain.

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September 2016
20150701toolboxinjectable
News / Toolbox

Injected into the brain, silicon net slyly spies on neurons

by  /  27 September 2016

A new injectable electronic mesh enables researchers to gently eavesdrop on the chatter of hundreds of neurons inside the brain.

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Gene geography: A novel trick reveals where in a mouse brain three different genes (colored dots) are active
News / Toolbox

Method maps position of thousands of active genes in brain

by  /  23 September 2016

A new technique acts as a genetic geolocator, pinpointing the precise location of genes that are expressed in the brain.

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Routine screen: New tests that analyze DNA from blood and saliva may one day help doctors screen for fragile X syndrome and related disorders.  BlindTurtle / iStock
News / Toolbox

Quick, cheap tests decode fragile X mutation

by  /  14 September 2016

An inexpensive new set of tests allows researchers to rapidly analyze the genetic glitch underlying fragile X syndrome.

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News / Toolbox

Chemical brew lets scientists see through bodies, brains

by  /  7 September 2016

A potent chemical cocktail renders tissue transparent in a way that makes even buried brain structures visible.

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Sample cells: Researchers can test potential drugs for fragile X syndrome using stem cells from people with the condition (left) that lack the fragile X protein (green).
News / Toolbox

Glowing cells bolster search for fragile X drugs

by  /  2 September 2016

A new genetic trick allows researchers to quickly spot the most promising treatments for fragile X syndrome among thousands of candidate compounds.

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August 2016
Hot links: A radioactive tracer that tags proteins in synapses (yellow) highlights the density of neuronal connections.
News / Toolbox

New tool spotlights neuron junctions in living human brains

by  /  19 August 2016

A new imaging technique allows researchers to illuminate the junctions between neurons in a living person’s brain.

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Fast forward:  Gene expression patterns in the monkey visual cortex (red box) are similar to those in people during infancy (top brains), childhood (bottom left) and adulthood (bottom right).
News / Toolbox

Maps reveal genetic landscape of developing monkey brain

by  /  12 August 2016

Researchers have charted gene expression in the brains of rhesus macaques from before birth into adulthood.

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Speed read: A new tool sorts neurons from the human brain into two broad types and 16 subtypes (colored dots) based on their gene expression profiles.
News / Toolbox

Software supplies snapshot of gene expression across brain

by  /  5 August 2016

A new tool provides speedy analysis of gene expression in individual neurons from postmortem brain tissue.

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July 2016
Dynamic duo: Two proteins (green) work together to fine-tune the activity of neurons in zebrafish.
News / Toolbox

Protein duo can tweak signaling balance among neurons

by  /  29 July 2016

A fusion of two proteins can silence the activity of specific neurons in the zebrafish spinal cord.

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Mighty merger: New software can sift and sort pieces of gene expression data gleaned from a microarray (left).
News / Toolbox

Online tool can mix, match gene expression data

by  /  22 July 2016

A new resource helps biologists easily mine large troves of information about when and where genes are expressed.

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