Spotted A roundup of autism papers and media mentions you may have missed.
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Spotted: Suramin surprise; film under fire

by  /  23 January 2015

January 19th

Suramin surprise

An antimicrobial drug called suramin improves behavior in a mouse model of fragile X syndrome, according to a study published last week in Molecular Autism. The drug, which has long been used to treat African sleeping sickness, blocks proteins on the cell surface that are thought to activate a ‘danger response.’ “When the cells activate their cell danger response, they can no longer devote all of their resources to normal cellular functions that might be required for neurodevelopment,” lead researcher Robert Naviaux, professor of medicine, pediatrics and pathology at the University of California, San Diego, told us last year after finding similar results in another mouse model. Suramin’s specific mechanism remains unclear, and its serious side effects warrant a healthy dose of caution about its promise in people.



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