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Features / Webinars

Sarkis Mazmanian explores probiotics for autism

12 June 2013
The Presenter

Sarkis Mazmanian

Principal Investigator, California Institute of Technology

On 12 June, Sarkis Mazmanian presented his lab’s work investigating the connection between gut bacteria, intestinal disease and autism — and how understanding this connection may lead to novel treatments for the disorder. Mazmanian is professor of biology at the California Institute of Technology in Pasadena, California.

You can watch a complete replay of the webinar above.

Use the comments section below to submit questions we didn’t have time to discuss during the Q&A session, or to pose follow-up questions for Mazmanian.

Press Policy
The Spectrum Webinar Series aims to facilitate the free exchange of ideas among autism researchers, including discussion of published and unpublished research, hypotheses and results. Members of the press may report information presented during a Spectrum webinar only if that material has already been published elsewhere or they have first obtained express written consent from the presenter.

About Webinars
Presentations by leading experts that showcase new findings, useful techniques and emerging topics in autism research. We invite questions before and during the presentations in the Comments section.
  • Paul Whiteley

    Very interesting prospect.

    Q1: Any details on the mechanism of ‘gut repair’? Purely an anti-inflammatory action?
    Q2: The nature of gut permeability: any clues about whether paracellular or transcellular?
    Q3: Zonulin? Was it measured, was it present and if so, was it affected?
    Q4: Playing devil’s advocate: were there any signs of a more systemic immune response to either B. fragilis or other gut bacteria as per evidence of bacterial translocation?


  • Payman

    Are any of these bacteria more activated at a certain time of the day… Could they have an off/on or dormant/active cycle at specifc time of the day?


  • sami

    what bacteria/species type to look for in probiotics?

    what medical/lab test i can ask the Dr to make to prove my child has leaky gut?

    why is leaky gut still considered quacky by many Drs?

    recommended botanicals/supplements?

    your take on raw camel milk?

    zonulin modulating drugs? when?

  • Mark Carew

    Have you any comment on the development phase relevent to gut,immunology and regressive type AS.
    many thanks.


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