Selective enzyme block reveals new treatment for fragile X
A drug that selectively blocks one form of an enzyme called GSK-3 prevents seizures and improves cognitive deficits in a mouse model of fragile X syndrome.
Society for Neuroscience 2017
A drug that selectively blocks one form of an enzyme called GSK-3 prevents seizures and improves cognitive deficits in a mouse model of fragile X syndrome.
A candidate drug in clinical trials for Huntington’s disease reverses gait problems in a mouse model of Rett syndrome.
Mouse pups exposed to an immune response in the womb show autism-like behaviors and altered gene expression in brain cells called microglia.
Researchers have used transcranial magnetic stimulation to show that people with fragile X syndrome have weak ‘inhibitory’ signals, those that dampen neuronal activity in the brain.
Spheres of brain cells derived from a fetal skull have gene expression patterns similar to those in brain tissue from the same fetus.
New artificial intelligence software can decode conversations between small monkeys called marmosets.
Some young children with autism excel on tests in which they must learn to connect visual cues.
Nonverbal children with autism don't show the typical wave of brain activity involved in linking objects with their names.
Mutations in the Rett syndrome gene MECP2 have different effects on subtypes of neurons.
A virus that delivers a working copy of the Rett syndrome gene to the brain improves features of the condition in mice, and appears to be safe in monkeys.