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Spectrum: Autism Research News

Author

Jessica Wright

Jessica Wright was senior news writer at Spectrum from 2010 to 2019. Her writing has also appeared in Nature and Scientific American.

Jessica has a Ph.D. in biological sciences from Stanford University.

April 2018
Two mice against black background

Altered brain waves may underlie social problems in autism mice

by  /  16 April 2018

Boosting the activity of a class of neurons that dampen brain signals eases social problems in a mouse model of autism.

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child with brain scan test

Top autism gene may alter sensory perception

by  /  16 April 2018

An unusual brain response to sound may distinguish children with mutations in SCN2A, a leading candidate gene for autism.

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extra neuronal connections may sprout from the amygdala, a brain region governing fear

In autism, brain’s emotion hub begins with too many cells

by  /  6 April 2018

The amygdala, a brain region that governs emotions, may be enlarged and overly connected in children with autism, but it shrinks as the children grow up.

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mutations in their mitochondrial genome

Mounting evidence links mitochondrial DNA to autism

by  /  5 April 2018

Genetic variants that affect mitochondria, the organelles that power cells, may increase the risk of autism.

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A cancer drug boosts levels of a key protein (red) in mice lacking SHANK3.

Cancer drug shows promise for treating some forms of autism

by  /  2 April 2018

A low dose of a drug used to treat lymphoma may ease social problems in some forms of autism.

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March 2018
Deleting DNA repeats from fragile X neurons restores expression (right, red) of the gene silenced in the syndrome.

CRISPR tweak fixes genetic flaw in fragile X syndrome

by  /  29 March 2018

A modified version of the genetic engineering tool CRISPR may restore expression of the gene mutated in fragile X syndrome.

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two children playing a game together

Race, income, education alter accuracy of autism screen

by  /  28 March 2018

Customized cutoff scores could boost the accuracy of a popular autism screen in certain populations.

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Mouse in a lab or maze hops around sniffing here and there

Why studying autism in mice may be doomed to fail

by  /  21 March 2018

After more than a decade of effort, scientists are questioning whether mouse models of autism can ever capture the social deficits seen in people with the condition.

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A mouse model of tuberous sclerosis (right) shows less protein synthesis in the brain than a control (left).

Shortage of proteins upends theory of tuberous sclerosis origins

by  /  14 March 2018

Mice with the mutations linked to tuberous sclerosis make too little protein in their brains — a finding that contradicts a leading theory about the condition.

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February 2018
child walking on stone path with parents' help

Genetics underscores importance of motor deficits in autism

by  /  28 February 2018

Spontaneous mutations that impair proteins may lead to motor problems in children with autism.

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