As the number of autism rodent models climbs, it is a good time for the field to step back and consider the best practices for assessing autism-like symptoms in rodents, says Jacqueline Crawley.
New standards for animal studies, including an emphasis on replicating results and the publication of negative findings, are vital for research progress, says Jacqueline Crawley.
Good mouse models of autism, and accurate tests to assay their phenotypes, are key to both narrowing down a cause and developing effective treatments, argues expert Jacqueline Crawley.